Anthony Weiner, ya know, the guy who sent pics of his swollen junk to women on twitter? Yeah, he announced on YouTube yesterday that he’ll be running for Mayor of New York City. Maybe he’ll move the Mayor’s Office to the red light district.

In the video, Weiner admitted some of his dimwitted decisions. “I made some big mistakes and I know I let a lot of people down, but I also learned some tough lessons.” So why run for mayor? “I’m running for mayor because I’ve been fighting for the middle class and those struggling to make it my entire life. And I hope I get a second chance.”

I think most everyone deserves a second chance. Weiner is no exception. I mean, hey… think of all the great joke opportunities. Some of our favorite late night hosts are on top of it.

Stephen Colbert:

“After withdrawing from public life Anthony Weiner is ready to stick it back in. Folks, that takes balls. Sadly, we know he has them.”

Conan O’Brien:

“Former Rep. Anthony Weiner? Remember him? He famously tweeted lewd photos of himself. He says he wants people to give him a second chance. Not in politics, but on instagram.”

Jimmy Fallon:

“Former Congressman Anthony Weiner said that he’s considering running for mayor of New York City. If nothing else, I’m sure that he’ll provide some stiff competition.”

“Come on, he’s the total package. I don’t want to be too hard on him. I don’t have a bone to pick with that guy.”

Jay Leno:

“Anthony Weiner, remember him? The Peter Tweeter? He’s now thinking of running for mayor of New York. And believe me, he has thought long and hard about this.”

Jimmy Kimmel:

“You know what’s funny? President Clinton had sex and lied about it, and he kept his job. Anthony Weiner didn’t have sex and lied about it, and lost his. I guess the lesson here is, if you’re gonna lie, have sex.”

David Letterman:

“When asked about the Congressman Weiner scandal, President Obama said that if it were him, he’d resign. When Bill Clinton was asked about the same thing he said, ‘If it was me, I wouldn’t be surprised.’”